Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - Histone Demethylase - GSK J4 hydrochloride

GSK J4 hydrochloride

CAS No. 1373423-53-0

GSK J4 hydrochloride ( —— )

Catalog No. M11540 CAS No. 1373423-53-0

GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 46 In Stock
5MG 75 In Stock
10MG 118 In Stock
25MG 215 In Stock
50MG 346 In Stock
100MG 524 In Stock
200MG 663 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    GSK J4 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM.
  • Description
    GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    JMJD3
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1373423-53-0
  • Formula Weight
    453.96
  • Molecular Formula
    C24H27N5O2·HCl
  • Purity
    >98%(HPLC)
  • Solubility
    Ethanol: 90 mg/mL warmed (198.25 mM); DMSO: 90 mg/mL warmed (198.25 mM)
  • SMILES
    CCOC(=O)CCNC1=NC(=NC(=C1)N1CCC2=CC=CC=C2CC1)C1=CC=CC=N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kruidenier L, et al. Nature, 2012, 488(7411), 404-408.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • KDM5-IN-48

    A potent, selective and orally bioavailable KDM5 inhibitor with biochemical IC50 of 15.1, 4.7 and 65.5 nM for KDM5A, KDM5B and KDM5C, respectively.

  • IOX1

    IOX1 is a potent, broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases.

  • LSD1-IN-7 benzenesul...

    LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.

Sign In Join Free